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HYLO NIGHT®
by Ursapharm
MEDICATION INSTRUCTIONS
Eye ointment
Apply before going to bed
Burning sensation
Sticky/foreign body sensation
Dry eye syndrome
Eyestrain
Long-term digital device use
6 months shelf life after opening
Without preservatives
Please store under 25ºc
IntroductionMedication Usage
HYLO NIGHT®
Understanding Dry Eyes Starts with the Tear Film
The tear film
is the outermost layer of the eye that constantly comes into contact with external irritants, helping to moisturize and protect the eyes.
The tear film consists of three layers,
each with its own unique functions
According to research reports, there are over 400 million dry eye syndrome patients worldwide, and the prevalence of dry eye syndrome continues to increase with age, with a sharp rise in patients around the age of 50. The causes of dry eye syndrome are commonly believed to be primarily associated with prolonged use of electronic devices, but in fact, there are numerous factors that can lead to dry eyes.
People at high risk for dry eye syndrome
People who stare at screens for a long time without enough blinking
People who wear contact lenses for a long time
Long-term drug uses, such as: vasoconstrictors, antidepressants,sleeping pills, blood pressure medications
Stay in a low humidity environment, such as: indoor places with air-conditioning or heating, or exposure to sunlight
Patients with immune system diseases, such as: arthritis, diabetes, thyroid disease
Women in Menopause (~over 45 years old)
Dry eye
Dry eye syndrome is not solely defined by insufficient tear secretion and can be broadly categorized into three types:
1.Aqueous-deficient type
This type occurs when the lacrimal glands degenerate, get damaged, or function abnormally, leading to reduced tear production.
2.Evaporative type
The meibomian glands, located at the base of the upper and lower eyelashes, are responsible for secreting oil and forming the lipid layer. A stable lipid layer helps reduce evaporation of the "aqueous layer." Insufficient secretion from the meibomian glands leads to continuous thinning of the lipid layer, resulting in rapid evaporation of the aqueous layer. This is often referred to as "meibomian gland dysfunction."
3.Mixed type
The majority of dry eye syndrome patients have a mixed type, which is characterized by a combination of the above two symptoms.
There are numerous methods to relief dry eyes, including artificial tears, light therapy, wearing specialized eyeglasses, and eye-protective nutrients, among others. Among these, the use of natural and preservative-free lubricating eye drops is the most common approach to relieving symptoms.
Sincerely recommend to those who experience the following issues
What is Vitamin A (Retinol Palmitate)?
Vitamin A is a well-known essential nutrient present naturally in healthy eyes and tear film. It plays a crucial role in regulating the proliferation and differentiation of corneal epithelial cells, protecting the conjunctiva and goblet cells. It is suitable for eye conditions such as dry eye, superior limbic keratoconjunctivitis, or conjunctivitis.
Vitamin A eye preparations:
can protect the eyes from free radicals, toxins, allergens, and inflammation. Research has shown that the topical use of Vitamin A (Retinol Palmitate) can be effective in treating dry eye syndrome.
Hylo-Night: Uninterrupted Eye Protection
During sleep at night, tear production ceases, leading to insufficient tear supply to the eyes.
This can potentially result in damage to the cornea and conjunctiva.
contains the oily substance Vitamin A (Retinol Palmitate)
which is a physiological component of the tear film. Vitamin A (Retinyl Palmitate) imparts a unique softness to the eye ointment, forming an even and stable lubricating protective film on the ocular surface that is less likely to be washed away.
protects the ocular surface and forms a stable layer together with the tear film
maintaining the health of the corneal and conjunctival epithelial cells.Designed specifically for ocular use, Hylo-Night is ideal for maintaining eye lubrication and comfort during the nighttime when artificial tears may not provide the desired effect.
not contain any medicinal ingredients
and serves as a smooth and comfortable ointment base that quickly dissolves to prevent dryness and discomfort.
The figure above shows the vitamin A in Hylo-Night has been proven to effectively improve tear film break-up time (TBUT), indicating its potential efficacy in addressing issues such as dry eyes.
Why are preservative eye drops being replaced?
Preservative eye drops were commonly used to prolong their shelf life. Preservatives not only eliminate microorganisms but can also damage the normal ocular surface tissue.
Long-term use of eye drops containing preservatives can be toxic to ocular surface cells, including corneal epithelium and conjunctiva. It can lead to corneal epithelial cell death, corneal punctate ulcers, delayed corneal wound healing, conjunctivitis/conjunctival fibrosis, unstable tear film, dry eye symptoms, allergic reactions, eye discomfort, and more.
The higher the concentration of preservatives, the more pronounced these side effects can become.
Preservative eye drops:
Preservatives not only have the ability to eliminate microorganisms but also to a limited extent disrupt the cell connections between corneal epithelial cells. The purpose is to facilitate the penetration of medications into the cornea. While this can enhance the local effect of the medication, it also reduces corneal epithelial cell activity and cell adhesion. Preservatives can also disrupt the lipid layer of the tear film, making the eyes more prone to dryness and discomfort.
Friendly Reminder: Before using this product, please consult a specialist or professional healthcare provider if you are an infant, child, or pregnant woman.
